Most Disruptive

The 100 most-disruptive inflammatory bowel disease papers of all time, ranked by the CD₅ disruption index over the NIH iCite citation graph.

Ranked from the IBDology fleet corpus, all IBD-surgery collections.
#PaperAltmetricCD index
1Post-surgical pyoderma gangrenosum of the vaginal vault associated with ulcerative colitis and Behçet's disease; a case report.
Lilford · 1989 · Eur J Obstet Gynecol Reprod Biol
+0.960
24 cites
2Long-term survival between total colectomy versus proctocolectomy in patients with FAP: a registry-based, observational cohort study
Ardoino · 2020 · Tumori
+0.818
20 cites
3Campylobacter colitis associated with erythema nodosum.
1982 · Br Med J (Clin Res Ed)
+0.763
29 cites
4Minimal surgery for chronic obstruction in patients with extensive or universal Crohn's disease.
Lee EC · 1982 · Ann R Coll Surg Engl
+0.760
214 cites
5Ileostomy in pregnancy.
Hudson · 1972 · Proc R Soc Med
+0.737
36 cites
6Surgical treatment of toxic megacolon. Ileostomy and colostomy to prepare patients for colectomy.
Turnbull · 1971 · Am J Surg
+0.730
120 cites
7Total colectomy and ileorectal anastomosis in diffuse ulcerative colitis.
AYLETT · 1957 · Br Med J
+0.703
34 cites
8Chronic ulcerative colitis associated with malignant disease. 1928.
Bargen JA · 1994 · Dis Colon Rectum
+0.690
20 cites
9Three hundred cases of diffuse ulcerative colitis treated by total colectomy and ileo-rectal anastomosis.
Aylett · 1966 · Br Med J
+0.636
137 cites
10Intra-abdominal "reservoir" in patients with permanent ileostomy. Preliminary observations on a procedure resulting in fecal "continence" in five ileostomy patients.
Kock · 1969 · Arch Surg
+0.589
474 cites
11ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents.
Levine A · 2014 · J Pediatr Gastroenterol Nutr
+0.557
1,109 cites
12AGA Clinical Practice Update on Surveillance for Hepatobiliary Cancers in Patients With Primary Sclerosing Cholangitis: Expert Review.
2019 · Clin Gastroenterol Hepatol
+0.550
79 cites
13Laparoscopic total proctocolectomy with creation of ileostomy for ulcerative colitis: report of two cases.
Peters · 1992 · J Laparoendosc Surg
+0.496
63 cites
14Ulcerative colitis treated by total colectomy and ileorectal anastomosis: a ten-year review.
AYLETT · 1963 · Proc R Soc Med
+0.424
39 cites
15Ankylosing spondylitis in a Canadian Indian population.
1966 · Ann Rheum Dis
+0.418
41 cites
16Predicting Outcomes in Pediatric Crohn's Disease for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease-Ahead Program.
Ricciuto A · 2021 · Gastroenterology
+0.418
77 cites
17Proctocolectomy without ileostomy for ulcerative colitis.
Parks A · 1978 · Br Med J
+0.400
1,028 cites
18Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis
Burke · 2020 · N Engl J Med
+0.371
60 cites
19Ulcerative colitis with relative sparing of the rectum. Clinical features, histology, and prognosis.
Spiliadis · 1987 · Dis Colon Rectum
+0.356
48 cites
20American Gastroenterological Association medical position statement: perianal Crohn's disease.
American Gastroenterological Association Clinical Practice Committee · 2003 · Gastroenterology
+0.325
134 cites
21Ileostomy for ulcerative colitis; technique, complications, and management.
WARREN · 1951 · Surg Gynecol Obstet
+0.314
136 cites
22An analysis of 10218 ulcerative colitis cases in China.
Jiang XL · 2002 · World J Gastroenterol
+0.296
134 cites
23Treatment of haemorrhoids in patients with inflammatory bowel disease.
Jeffery PJ · 1977 · Lancet
+0.295
70 cites
24Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease.
Hellers · 1980 · Gut
+0.292
364 cites
25Surgical treatment of ulcerative colitis.
CATTELL · 1948 · JAMA
+0.283
33 cites
26Life expectancy after colectomy and ileorectal anastomosis for familial adenomatous polyposis.
Nugent · 1993 · Dis Colon Rectum
+0.270
148 cites
27SQUAMOUS CELL CARCINOMA OF THE RECTUM COMPLICATING ULCERATIVE COLITIS: REPORT OF TWO CASES.
1964 · Mayo Clin Proc
+0.250
36 cites
28Extended use of sodium tetradecyl sulfate in treatment of hemangiomas and other related conditions
Woods · 1987 · Plast Reconstr Surg
+0.226
39 cites
29Results of a survey to evaluate whether vaginal delivery and episiotomy lead to perineal involvement in women with Crohn's disease.
Brandt LJ · 1995 · Am J Gastroenterol
+0.225
74 cites
30An Update on the Medical Management of Inflammatory Pouch Complications
Quinn · 2020 · Am J Gastroenterol
+0.221
30 cites
31Predicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease-Ahead Program.
Orlanski-Meyer · 2021 · Gastroenterology
+0.218
48 cites
32["Strictureplasty" in Crohn disease].
Alexander-Williams J · 1982 · Chirurg
+0.212
23 cites
33Anorectal tuberculosis.
Logan VS · 1969 · Proc R Soc Med
+0.208
66 cites
34Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: an indication for colectomy.
Blackstone · 1981 · Gastroenterology
+0.207
413 cites
35The relative significance of preoperative oral antibiotics, mechanical bowel preparation, and preoperative peritoneal contamination in the avoidance of sepsis after radical surgery for ulcerative colitis and Crohn's disease of the large bowel.
Barker · 1971 · Br J Surg
+0.205
57 cites
36Effects of Primary Sclerosing Cholangitis on Risks of Cancer and Death in People With Inflammatory Bowel Disease, Based on Sex, Race, and Age.
2020 · Gastroenterology
+0.198
148 cites
37Primary resection of the colon in acute ulcerative colitis.
RIPSTEIN · 1953 · JAMA
+0.188
21 cites
38The role of colonoscopy in the differential diagnosis of inflammatory bowel disease.
Waye JD · 1977 · Gastrointest Endosc
+0.185
74 cites
39Prevalence of primary sclerosing cholangitis in patients with ulcerative colitis.
1991 · Gastroenterology
+0.175
311 cites
40OCULAR COMPLICATIONS OF ULCERATIVE COLITIS.
1964 · Am J Ophthalmol
+0.166
39 cites
41Treatment of colorectal and ileoanal anastomotic sinuses
Whitlow · 1997 · Dis Colon Rectum
+0.166
55 cites
42Comparison of handsewn with stapled loop ileostomy closures
Hull · 1996 · Dis Colon Rectum
+0.161
58 cites
43Risk factors for recurrence of primary sclerosing cholangitis of liver allograft.
2002 · Lancet
+0.156
163 cites
44Hyperalimentation as primary therapy for inflammatory bowel disease.
Fischer · 1973 · Am J Surg
+0.154
153 cites
45The role of microRNA-16 in the pathogenesis of autoimmune diseases: A comprehensive review.
2019 · Biomed Pharmacother
+0.150
48 cites
46Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery.
Rutgeerts P · 1984 · Gut
+0.144
639 cites
47Course of ulcerative colitis: analysis of changes in disease activity over years.
Langholz · 1994 · Gastroenterology
+0.142
526 cites
48The effects of diversion of intestinal contents on the progress of Crohn's disease of the large bowel.
Burman JH · 1971 · Gut
+0.141
93 cites
49High serum tumor necrosis factor-alpha levels are associated with lack of response to infliximab in fistulizing Crohn's disease.
Martínez-Borra J · 2002 · Am J Gastroenterol
+0.138
93 cites
50Repair of persistent perineal sinuses by means of a pedicle flap of musculus gracilis. Case report.
Bartholdson · 1975 · Scand J Plast Reconstr Surg
+0.135
41 cites
51Toxic megacolon.
1973 · Dis Colon Rectum
+0.135
20 cites
52Pouch advancement and neoileoanal anastomosis for anastomotic stricture and anovaginal fistula complicating restorative proctocolectomy
Fazio · 1992 · Br J Surg
+0.134
60 cites
53Surgical measures as supplements to the management of idiopathic ulcerative colitis; cancer, cirrhosis, and arthritis as frequent complications.
DENNIS · 1952 · Surgery
+0.133
84 cites
54The treatment of acute toxic ulcerative colitis by ileostomy and simultaneous colectomy.
CRILE · 1951 · Gastroenterology
+0.130
50 cites
55Predictability of the postoperative course of Crohn's disease.
Rutgeerts P · 1990 · Gastroenterology
+0.129
1,460 cites
56Emerging role of IL-35 in inflammatory autoimmune diseases.
2018 · Autoimmun Rev
+0.129
78 cites
57Prospective, randomized trial comparing laparoscopic vs. conventional surgery for refractory ileocolic Crohn's disease.
Milsom · 2001 · Dis Colon Rectum
+0.127
247 cites
58Faecal markers of gastrointestinal inflammation.
Sherwood RA · 2012 · J Clin Pathol
+0.127
47 cites
59Ileorectal anastomosis: review 1952-1968.
Aylett · 1971 · Proc R Soc Med
+0.126
39 cites
60Ocular changes in granulomatous ileocolitis.
1970 · Arch Ophthalmol
+0.126
46 cites
61Quality of life after prophylactic colectomy and ileorectal anastomosis in patients with familial adenomatous polyposis
Church · 1996 · Dis Colon Rectum
+0.124
53 cites
62Paradoxical gastrointestinal effects of interleukin-17 blockers.
2020 · Ann Rheum Dis
+0.123
209 cites
63Fate of the rectal mucosa after rectal mucosectomy and ileoanal anastomosis.
Heppell · 1983 · Dis Colon Rectum
+0.121
105 cites
64Portal bacteraemia in cases of ulcerative colitis submitted to colectomy.
Eade · 1969 · Lancet
+0.118
90 cites
65Endoscopic balloon dilation of colonic and ileo-colonic Crohn's strictures: long-term results.
Breysem Y · 1992 · Gastrointest Endosc
+0.118
93 cites
66An innovative technique for colorectal specimen retrieval: a new era of "natural orifice specimen extraction" (N.O.S.E)
Palanivelu · 2008 · Dis Colon Rectum
+0.117
113 cites
67Symposium. Crohn's disease: anal lesions.
Lockhart-Mummery HE · 1975 · Dis Colon Rectum
+0.116
76 cites
68Effects of orthotopic liver transplantation and immunosuppression on inflammatory bowel disease in primary sclerosing cholangitis patients.
1993 · Transplant Proc
+0.115
49 cites
69Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications.
Riddell · 1983 · Hum Pathol
+0.113
1,590 cites
70Cyclosporine in severe ulcerative colitis refractory to steroid therapy.
Lichtiger · 1994 · N Engl J Med
+0.110
1,435 cites
71Serum antibodies to Bacteroides species in chronic inflammatory bowel disease.
Tvede · 1983 · Scand J Gastroenterol
+0.109
42 cites
72THE COURSE AND PROGNOSIS OF ULCERATIVE COLITIS. III. COMPLICATIONS.
1964 · Gut
+0.109
464 cites
73Choice of operation for the toxic megacolon phase of nonspecific ulcerative colitis.
Turnbull · 1970 · Surg Clin North Am
+0.106
42 cites
74Mortality in patients with familial adenomatous polyposis.
Arvanitis · 1990 · Dis Colon Rectum
+0.105
325 cites
75The fate of ileorectal anastomosis in Crohn's disease.
Burman · 1971 · Gut
+0.104
57 cites
76Sclerosing cholangitis after continuous hepatic artery infusion of FUDR.
1985 · Ann Surg
+0.103
135 cites
77AIDS complicated by syphilis can mimic uveitis and Crohn's disease. Case report.
1987 · Arch Ophthalmol
+0.102
22 cites
78Primary sclerosing cholangitis: a review of its clinical features, cholangiography, and hepatic histology.
Chapman RW · 1980 · Gut
+0.102
740 cites
79Subtotal colectomy for ulcerative colitis: complications related to the rectal remnant.
Carter F · 1991 · Dis Colon Rectum
+0.101
75 cites
80Influence on sexual function of abdominoperineal resection for ulcerative colitis.
STAHLGREN · 1958 · N Engl J Med
+0.100
40 cites
81Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis.
2003 · Rheumatol Int
+0.099
639 cites
82The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients.
Greenstein · 1976 · Medicine (Baltimore)
+0.099
1,063 cites
83Social prognosis in patients with ulcerative colitis.
Hendriksen · 1980 · Br Med J
+0.097
51 cites
84Anal complications in Crohn's disease.
Williams DR · 1981 · Dis Colon Rectum
+0.095
156 cites
85Single-patient randomised clinical trial. Use in determining optimum treatment for patient with inflammation of Kock continent ileostomy reservoir
McLeod · 1986 · Lancet
+0.093
68 cites
86Primary closure of perineal wound after proctocolectomy or rectal excision.
Hultén · 1971 · Acta Chir Scand
+0.093
36 cites
87The Pathogenesis of Extraintestinal Manifestations: Implications for IBD Research, Diagnosis, and Therapy.
2019 · J Crohns Colitis
+0.092
173 cites
88Laparoscopically assisted ileocolectomy in Crohn's disease.
Milsom · 1993 · Surg Laparosc Endosc
+0.091
77 cites
89Active ulcerative colitis associated with low prevalence of Blastocystis and Dientamoeba fragilis infection.
Petersen AM · 2013 · Scand J Gastroenterol
+0.090
82 cites
90Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas.
1991 · Hum Pathol
+0.089
466 cites
91The Prevalence and Incidence of Axial and Peripheral Spondyloarthritis in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
2017 · J Crohns Colitis
+0.089
167 cites
92Aetiology of disruption of intestinal anastomoses.
Irvin · 1973 · Br J Surg
+0.088
326 cites
93Preliminary experience with laparoscopic intestinal surgery for Crohn's disease.
Ludwig · 1996 · Am J Surg
+0.084
99 cites
94The OMGE multinational inflammatory bowel disease survey 1976-1986. A further report on 3175 cases.
Myren J · 1988 · Scand J Gastroenterol Suppl
+0.084
22 cites
95Inflammatory bowel disease.
Hyams Jeffrey · 2005 · Pediatr Rev
+0.084
26 cites
96Histological diagnosis of chronic inflammatory bowel disease in childhood.
Chong SK · 1985 · Gut
+0.083
100 cites
97Paradoxical puborectalis contraction in patients after pelvic pouch construction
Hull · 1995 · Dis Colon Rectum
+0.080
27 cites
98Laparoscopic surgery for inflammatory bowel disease
Liu · 1995 · Am Surg
+0.078
45 cites
99Pregnancy in the patient with ileostomy and colectomy.
PRIEST · 1959 · JAMA
+0.077
22 cites
100Risk factors for intra-abdominal sepsis after surgery in Crohn's disease.
Yamamoto T · 2000 · Dis Colon Rectum
+0.077
281 cites